Run in-silico clinical trials
Skills for quantitative systems pharmacology using Jinkō platform. Support the full modeling workflow: gathering evidence and observed data, building and calibrating models, estimating uncertainty, running sensitivity analyses, creating virtual populations, simulating clinical trials, visualizing results, and producing analysis.
Skills 20 in the ChatGPT listing
Jinkō Modeling Discover and route Jinkō QSP and mechanistic-modeling requests to the public Jinkō skill that owns the work. Jinkō CMA-ES Calibration Create, run, poll, and inspect results for Jinkō CMA-ES calibrations via the jinko-sdk: attach data tables and/or an advanced output set as fitness-function sources, set CMA-ES options and parameter priors, launch and monitor the run, and read performance/results payloads. Jinkō Vpop Subsampling Create, validate, run, inspect, reuse, and edit Jinkō virtual-population subsampling designs with the jinko-sdk. Jinkō Context Explain core Jinkō context, navigation, version management, and domain language for agents and users. Jinkō Data Tables Create or inspect Jinkō data tables via the jinko-sdk. Jinkō Documents Create or update a Jinkō document from markdown through the jinko-sdk, including headings, tables, code blocks, links to Jinkō project items, uploaded images, and links to existing Jinkō References. Jinkō Models Build or edit a Jinkō computational model (QSP/PK-PD) via the jinko-sdk: parameters, categorical parameters, compartments, species, ODEs, reactions, dosing events, algebraic rules, baseline checks, solving options, units, and component tags. Jinkō Output Sets Create, inspect, validate, and incrementally edit Jinkō output sets via the jinko-sdk: simple output sets (measure designs) that list scalar measures derived from model outputs, and advanced output sets (scoring designs) that define constraints, scalars, and weighted objectives for scoring virtual populations. Jinkō Protocols Design or edit multi-arm Jinkō protocol designs via the jinko-sdk. Jinkō References Create, inspect, download, and organize Jinkō reference PDFs and their extracts through the jinko-sdk. Jinkō SDK Setup Authenticate and configure access to a Jinkō project via the jinko-sdk. Jinkō Solution Guide The jinko-solution-and-product-guide skill provides users with clear, concise information about solutions (services capabilities) and product features in jinko to solve the users scientific and modeling objectives. Jinkō CMA-ES Task Execute a CMA-ES calibration from confirmed Jinkō inputs: assemble the model, protocol, output sets, fitness data tables, parameter priors, and optimizer options; create and run the Calibration; and return the supported results. Define Calibration Parameters Classify directly valued Jinkō model inputs by evidence source and assign inputs needing calibration to explicit calibration steps. Extract Jinkō Data Extract or digitize reported biomedical values from papers, figures, tables, supplements, images, or web sources into traceable CSV/Markdown, optionally as a calibration-ready Jinkō data table. Biomedical Literature Search Find and shortlist biomedical publications from PubMed for knowledge, data, or reusable-model evidence. Clinical Trial Data Scoping Find and shortlist ClinicalTrials.gov registry and posted-results records for biomedical modeling evidence. Jinkō Trials Create, sanity-check, run, poll, and download results for Jinkō in-silico trials via the jinko-sdk. Jinkō Trial Visualizations Create, update, inspect, sanity-check, and retrieve Jinkō TrialVisualization project items for completed or running trials. Jinkō Virtual Populations Create, generate, inspect, or work with Jinkō virtual populations (vpops) and vpop designs via the jinko-sdk. 
LatchBio#276
Inductive Bio#285